Apoptosis

Apoptosis Phagocytosis Phosphatidyl serine (PS) normally on the home(a) leaflet of the plasma create from raw stuff layer flips to the outer leaflet Engulfing phagocyte PS sensory receptor (CDI4?) DOCK I80 (CED5 homolog) *CD36 Croquemort (drosophila) Contains SH3 creation which allows interaction with signaling pathways dominion of cytoskeleton and stall motility ? * affection molecules which clog TSP and signal via tyrosine kinases Mitochondria Bax Pro-apoptotic Bcl-2 family members promote, and anti-apoptotic Bcl-2 family members squeeze mitochondrial cytochrome c release The Bcl-2 Family C Ligand ( tumour slough calculate) (trimer, contact residues in red) N tumor necrosis factor out TNF receptor (TNFR) (monomer, cysteines in yellow, contact residues in red) TNF-family death receptors FasL TRAIL TRAIL Anti-apoptotic Bcl-2, Bcl-x L, Mcl-I Bcl-w, A-I BH4 BH4 BH3 BH3 BHI BHI BH2 BH2 TM TM TNFR Fas TRAIL-RI TRAIL-R2 Cytochrome c TSP, macrophage secreted glycoprotein which provides a bridge between the macrophage and an apoptotic cellular phone Exposure of sugar residues on cell-surface carbohydrates Pro-apoptotic Apoptosome Apaf-I Caspase-9 tetramer Procaspase-9 Bcl-x L blocks?

Bik, Hrk, Bim, Blk Bad, Bid BH3 BH3 TM Death effector plain Death body politic TNF Tumor necrosis factor TRAIL TNF-related apoptosis-inducing ligand TRADD TNF-receptor-associated death domain FADD Fas-associated death domain TRAF TNFR-associated factor IAP Inhibitor of apoptosis protein Caspases3,6,7 Bax, Bak, Mtd/Bok Bcl-x S BH4 BH3 BHI BH2 TM Death domain TRAF- I TRAF-2 c-IAP Inhibits TNFinduced apoptosis FADD TRADD Recruits and permits caspase-8 transactivation Recruits and permits caspase-8 transactivation FADD Thrombospondin (TSP) moiety PS? *?vB3 Ion flux ATP CDI4 Plasma membrane-bound glycoprotein which binds lipid molecules ABC Transporter (CED7 homolog) employ in phagocytosis unclear BH4 BH3 TM ? Unknown adapter recruits and permits caspase-8 transactivation Apoptotic cell Lectins...If you want to get a full essay, order it on our website: Ordercustompaper.com

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